Kwan SH, Abdul Aziz NH, Ismail MN. The stripped snakehead fish possesses wide range of medicinal properties. Analytical Biochemistry Research Centre (ABrC), Universiti Sains Malaysia, USM, 11800, Penang, Malaysia, Journal Name: The Natural Products Journal. and shortened the duration of wound healing [20]. The snakehead (Channa striata) extract contains albumin (in its water phase) and omega-3 and omega-6 (in its oil phase) which have been proven to be effective in wound healing process. (Channa Striata) and the effect of Snakehead fish consumption (Channa Striata) on postpartum maternal perineal wound healing i.e. The process of extraction began in 2001 and in 2003 it was used to support applications in hospital diet. the fish, and their therapeutic effects are being studied.The C. striata have exhibited antibacterial, antinociceptive and 2020 Jan 1;27(1):48-59. Discovery of Channa striata extracts as regenerative medicine in promoting wound healing and scarless skin regeneration Haruan, Channa striatus, is a snakehead fish consumed in many parts of the southeast Asian region. Soon Hong Kwan and Mohd Nazri Ismail*, “Discovery of Channa Striata Extracts as Regenerative Medicine in Promoting Wound Healing and Scarless Skin Regeneration”, The Natural Products Journal (2020) 10: 1. https://doi.org/10.2174/2210315510999200629205601, Medical Biotechnology Laboratory, Central Research Laboratories, Faculty of Medicine, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia, Analytical Biochemistry Research Centre (ABrC), Universiti Sains Malaysia, USM, 11800, Penang, Malaysia, Phytochemical Investigation and Antimutagenic Potential of Ethanolic Extracts of Emblica officinalis, Terminalia chebula and Terminalia bellirica. The Natural Products Journal, 2020. SH Kwan, MN Ismail. It could be … Bioactive Proteins in Channa striata Promote Wound Healing through Angiogenesis and Cell Proliferation. This paper aims to describe the nutrients profile of Channa striata extract and their role in health. The results showed that snakehead fish extract giving had an effect on blood leukocytes number with p-value of 0.003. The purpose of this study is to assess the effect of haruan extract on wistar rat’s buccal mucosa wound healing on day 3, 5, and 7 histopathologically. Haruan ( Channa striatus) is a type of fresh water fish in Malaysia that is known to promote wound healing. The ability of striatin in inducing wound healing is suggested through ability to increase the growth of fibroblast cells. Keywords: Channa striata, fish, medicine, natural product, skin regeneration, scarless, wound healing, Title:Discovery of Channa Striata Extracts as Regenerative Medicine in Promoting Wound Healing and Scarless Skin Regeneration, Author(s):Soon Hong Kwan and Mohd Nazri Ismail*, Affiliation:Medical Biotechnology Laboratory, Central Research Laboratories, Faculty of Medicine, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Analytical Biochemistry Research Centre (ABrC), Universiti Sains Malaysia, USM, 11800, Penang, Keywords:Channa striata, fish, medicine, natural product, skin regeneration, scarless, wound healing. Efficacy of snakehead fish (Channa striatus) in subjects with allergic rhinitis: a randomized controlled trial. Snakehead fish (Channa striata)extract has been introduced and significantly proven to increase levels of albumin in hypoalbuminemia and to accelerate the process of wound healing in postoperative patients. Utilization of Pasuruan Channa striata in Malang has been started since 1999, with the design of the extraction tool. understanding of the species, which provide a promising future for drug development. View 0 peer reviews of Bioactive Proteins in Channa striata Promote Wound Healing through Angiogenesis and Cell Proliferation on Publons COVID-19 : add an open review or score for a COVID-19 paper now to ensure the latest research gets the extra scrutiny it needs. Some of the immune molecules that have been characterized in Channa striatus includes Chemokine, Chemokine receptors, Thioredoxin, Superoxide dismutase, Serine Protease, Cathepsin, Lectin. Susibalan BD, Abdullah B, Lazim NM, Kadir AA. 2020 Jan 1;27(1):48-59. medicine which could complement modern medicine in promoting human health. Sig (2-tailed) values of 0.000 <0.05. lot of progress in characterising the biomolecules of this fish. the fish, and their therapeutic effects are being studied.The C. striata have exhibited antibacterial, antinociceptive and Susibalan BD, Abdullah B, Lazim NM, Kadir AA. In view of traditional use of C. striatafor wound healing, the present study was undertaken to investigate the beneficial effects of orally administered freeze dried aqueous extract of Channa striata(AECS) in experimentally induced gastric ulcers in Wistar rats. This is an open access article under the CC–BY-SA license. in the Asian region for its medicinal properties, particularly in wound healing. Against T47D Human Breast Cancer Cell, Antioxidant and Enzyme Inhibitory Properties of Mangifera indica leaf Extract. Abstract The snakehead (Channa striata) contained fatty acids omega-3 and omega-6 are useful as nutrients in accelerating the wound healing process. Antioxidant Capacity, Phytochemical Analysis and Identification of Active Compounds in Anchomanes difformis, Cytotoxic Constituents from the Bark of Erythrina poeppigiana Against the MCF-7 Breast Cancer Cell Lines, Microwave Facilitated Green Synthesis and Characterization of Acrylamide Grafted Copolymer of Kheri (Acacia chundra) Gum Polysaccharide, Identification of Bioactive Coumarin(s) from Three Endophytic Fungal Species of Calophyllum tomentosum, Antioxidant and Cytotoxicity Activity of Phenolic Compounds from Piper sarmentosum Roxb. recovery were identified in the species. The applications of C. striata extracts by 0 mm and extending beyond exposure area), Respiratory depth a = increased, b = decreased, Motor activity a = increased, b = decreased, Convulsion a = tonic, b = clonic, c = mixed. Snakehead fish (Channa striata) have high albumin content, a protein needed for cell development and the formation of new tissue.The aim of this study was to determine the influence of snakehead fish extract emulgel given topically on incision wounds in white rats. During wound healing process, much more energy is needed to repair cell and tissue disruptions. Channa striatus rely on their innate immune components to fight against these infections. Wound dressing with thermal stability is highly desired for burns healing. Active Subfractions, Phytochemical Constituents, Dipeptidyl Peptidase-IV Inhibitory Activity and Antioxidant of Leaf Extract from Hibiscus surattensis L. DAILY USAGE DOSE OPTIMATION OF OINTMENT, EMULSION, AND OINTMENT- EMULSION COMBINATION OF SNAKEHEAD FISH (CHANNA STRIATA BLOCH) EXTRACT FOR WOUND HEALING STAGE II ON WISTAR STRAIN WHITE MALE RATS (RATTUS NORVEGICUS) Mohamad Andrie and Wintari Taurina* Department of Pharmacy, Faculty of Medicine, Tanjungpura … The average wound healing occurred on the 8th day with p-value of 0.001. Based on the above results it could be concluded that snakehead fish extract giving of 700 mg 21 for 7 days to postoperative caesarian sectio patients had an effect to the blood leukocytes number and wound healing. effective wound recovery property through various pharmacology assays. Besides, the approaches towards scarless wound in future 2020: Bioactive Proteins in Channa striata Promote Wound Healing through Angiogenesis and Cell Proliferation. Author(s): The aims of this work were the extraction of collagen Type-I from snakehead fish skin (Channa striata) and crosslinking collagen with alginate. With the advancement of technology, researchers have made a Based on the above results it could be concluded that snakehead fish extract giving of 700 mg 2 1 for 7 days to postoperative caesarian sectio patients had an effect to the blood leukocytes number and wound healing Various types of bioactive molecules have been identified in recovery were identified in the species. Channa striata (also known as Channa striatus) is an air-breathing freshwater snakehead fish which is well known through menu has positively correlated to postoperative wound healing [19]. Purpose:The purpose of this study is to determine the effect of extract Haruan (Channa striata) 25%, 50%, and 100% in wound healing process of buccal mucosa Wistar (Rattus norvegicus) Rats on day 3 by counting the number of neutrophils every treatment groups. Many biomolecules associated with antibacterial and antinociceptive properties, which are crucial for healthy wound Wound healing is a complex phenomenon that results in the treatment of anatomic continuity and function, accomplished by several processes involving the orderly sequence of biological events such as inflammation, cell migration, angiogenesis, provisional matrix synthesis, collagen deposition and re-epithelization,.The wound healing … The rat’s skin was wounded to produce acute stage II opened wound… Challenges and solutions to develop an aquatic-derived drug practitioners in treating different illnesses are discussed. The other example of natural antibiotics is garlic (effective against Salmonella and E.coli). As topical preparation, Haruan spray needs to be evaluated in terms of the possibility to cause irritation reaction or toxic response. 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